GLP-1 Weight Loss Programs: Full Side-by-Side Comparison
We compared Calibrate, Ro Body, Found, Hims & Hers, and Sprout across 5 criteria — clinical effectiveness, cost, comprehensiveness, accessibility, and patient satisfaction. Here's what we found.
Last updated March 2026 · Read our methodology
Your GLP-1 Program Comparison Guide
Finding the right GLP-1 weight loss program means balancing multiple factors: cost, medication options, coaching support, medical oversight, and accessibility. No single program is "best" for everyone—your choice depends on your health profile, budget, and lifestyle preferences.
Use our side-by-side comparison below to understand how the top programs stack up, then click through to detailed reviews of each provider.
Updated February 2026. No sponsored placements. Independent scoring based on patient reviews, clinical efficacy data, pricing analysis, and accessibility metrics.
All 5 Programs at a Glance
Click on any program name below to read the full review.
| Program | Price Range | Medications | Coaching | Best For |
|---|---|---|---|---|
| Calibrate | ~$1,649/year | Brand GLP-1s | Included (1:1) | Clinical intensity, insurance coverage |
| Ro Body | $99-199/month | Brand & compound | Add-on available | Affordability, flexibility |
| Found | $199-299+/month | Brand GLP-1s | Included (personalized) | Holistic support, brand meds |
| Hims & Hers | $99-199/month | Compounded semaglutide | Minimal | Budget-conscious, simplicity |
| Sprout Health | $199-249/month | Brand & compound | Coaching included | Mid-range pricing, flexibility |
Pricing Breakdown
Calibrate: ~$1,649/year (all-inclusive). If you have insurance, costs can drop significantly. Many major insurance carriers cover Calibrate with proof of clinical obesity (BMI ≥30 or ≥27 with comorbidity).
Ro Body: $99/month (~$1,188/year base). Medications are additional, ranging from $200–$500/month depending on your GLP-1 selection and dosage. Add-on services (coaching, labs) increase costs.
Medications & Supply
Both programs offer access to GLP-1s, but the source differs:
Calibrate: Brand-name GLP-1s (semaglutide for diabetes/weight loss, tirzepatide). Pharmacy-filled via major networks.
Ro Body: GLP-1s from Ro Pharmacy. Mix of brand and compounded options, with direct shipping to your door.
Overall Winner
Calibrate wins for: Medical oversight, insurance integration, dedicated coaching, complex cases.
Ro Body wins for: Affordability, accessibility, speed of enrollment, autonomy.
Choose Calibrate if you want a comprehensive, medically rigorous program with expert oversight and coaching. Choose Ro Body if cost, speed, and simplicity matter most.
How to Choose Your Program
Step 1: Assess Your Budget
Programs range from $99/month (Hims & Hers, Ro Body) to $1,649/year all-inclusive (Calibrate). Decide what monthly or annual spend feels sustainable long-term.
Step 2: Medication Preference
Prefer brand-name? Calibrate, Found, and Sprout offer name-brand GLP-1s. Open to generic/compounded? Ro Body and Hims & Hers are cheaper with compounded semaglutide.
Step 3: Support Level
Want intensive coaching? Calibrate and Found excel here. Prefer independence? Ro Body and Hims & Hers get out of your way.
Step 4: Use the Quiz
Take our 2-minute quiz to get personalized program recommendations based on your unique situation.
Detailed Program Reviews
Read the full breakdown of any program you're considering:
- Calibrate Review — Comprehensive analysis of Calibrate's clinical model, pricing, and outcomes.
- Ro Body Review — Complete guide to Ro Body's affordability and app-first approach.
- Found Review — Deep dive into Found's holistic coaching and brand medication focus.
- Hims & Hers Review — Analysis of Hims & Hers' budget-friendly model and what you get.
- Sprout Health Review — Evaluation of Sprout Health's mid-market positioning and flexible approach.
Comparison: Calibrate vs Ro Body
Two of the most popular programs head-to-head. Read the full Calibrate vs Ro Body comparison →
Comparison: Found vs Hims & Hers
Holistic coaching vs. budget simplicity. Read the full Found vs Hims & Hers comparison →
Drug Comparison: Ozempic vs Mounjaro
The two leading GLP-1/GIP medications explained. Read the full Ozempic vs Mounjaro comparison →
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