Getting Started

You've Done the Research. Let's Get You Started.

Starting a GLP-1 program is simpler than you think. Here's exactly what happens, what it costs, and which programs we recommend after reviewing all 9.

Quick answer: Getting started on GLP-1 therapy requires a consultation with a qualified provider, understanding eligibility criteria, and preparing for common side effects like nausea. Most people begin with 0.25mg weekly and gradually increase.

What to Expect

A realistic timeline from your first evaluation to results

Week 1

Complete Your Health Evaluation

You complete an online health evaluation (5 minutes). A licensed physician reviews your profile and prescribes medication if appropriate.

Week 2

Medication Arrives & You Start Low Dose

Your medication arrives by mail. You start at a low dose to minimize side effects. Most people notice reduced appetite within days.

Month 1

Early Weight Loss Begins

Average weight loss of 3–5 lbs. Cravings significantly reduced. Some GI side effects are normal and usually resolve.

Month 3

Momentum Builds

Average weight loss of 12–18 lbs. Energy levels improve. Most side effects have stabilized.

Month 6+

Sustained Results & Health Improvements

Average weight loss of 25–35 lbs. Health markers (blood pressure, A1C, cholesterol) often improve significantly. Based on STEP and SURMOUNT clinical trial data. Individual results vary.

Our Top 3 Recommendations

Just three choices. Decision fatigue is the enemy.

8.1

Ro Body

$199–$299/mo

Our highest-rated program overall. Compounded semaglutide, all 50 states, streamlined online experience. If you're not sure where to start, start here.

Start with Ro Body → Read our full review →

7.6

Found

$99–$199/mo

The most affordable GLP-1 program available. Accepts insurance, offers oral tablets if you prefer not to inject. Great for getting started without a big commitment.

Start with Found → Read our full review →

7.8

Calibrate

$249–$349/mo

A comprehensive program with metabolic coaching, behavioral support, and strong insurance coverage. Best for people who want a full care team alongside medication.

Start with Calibrate → Read our full review →

Common Questions Before Starting

Real answers to help you get started with confidence

Do I need a BMI of 30 to qualify? +

Most programs require BMI 27+ with comorbidities or 30+. Some are more flexible. A licensed provider will review your health history and make the final determination during your free evaluation.

What if it doesn't work for me? +

Programs like Remedy Meds offer money-back guarantees. Most programs let you cancel anytime without penalty. Many also offer medication adjustments or switching options if your initial dose isn't right.

Is compounded semaglutide safe? +

Compounded semaglutide contains the same active ingredient as the FDA-approved Wegovy. Learn more about compounded vs. brand semaglutide here. Availability changes frequently in 2026, so confirm status before enrolling.

Can I use my insurance? +

Calibrate, Found, and Sprout accept insurance. Others are cash-pay with savings programs. See our guide to insurance coverage for program-by-program details.

The hardest part is starting.

Every program on our list offers a free initial evaluation — you won't pay anything until a physician confirms you're a good candidate.

See Our Top-Rated Program →

or compare all 9 programs →

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